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Actinomycin D

Inh 50-76-0 2-Amino-N,N'-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide

产品编号 ABIN1027831

发货至: 中国

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Quick Overview for Actinomycin D (ABIN1027831)

应用范围

Inhibition (Inh)

Chemical Name

2-Amino-N,N'-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide

原理

Transcription inhibitor

产品特性

Transcription inhibitor.

纯度

>98 %

Formula

C62H86N12O16

Solubility

Soluble to 50 mM in DMSO
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说明

Source: Synthetic.
Appearance: White Solid

限制

仅限研究用
状态

Solid

注意事项

Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin R40 - Limited evidence of a carcinogenic effect R62 - Possible risk of impaired fertility Hazard Phrases: H300 - Fatal if swallowed Precautionary Phrases: P264 -P301 + P310

注意事项

Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin R40 - Limited evidence of a carcinogenic effect R62 - Possible risk of impaired fertility Hazard Phrases: H300 - Fatal if swallowed Precautionary Phrases: P264 -P301 + P310

储存条件

-20 °C
背景

The actinomycins are a class of polypeptide antibiotics. Actinomycin D inhibits transcription by binding DNA at the transcription initiation complex and preventing elongation by RNA polymerase. Actinomycin D has been used as a chemotherapy drug, and an antibiotic.

分子量

1255.43

CAS-编号

50-76-0