The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008].
custom-made
ING3
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
ING3
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
inhibitor of growth family member 3 (ING3) 蛋白 inhibitor of growth family, member 3 (Ing3) 蛋白 inhibitor of growth protein 3 (CpipJ_CPIJ009396) 蛋白 inhibitor of growth family, member 3 (ing3) 蛋白 inhibitor of growth family member 3 L homeolog (ing3.L) 蛋白 1300013A07Rik 蛋白 Eaf4 蛋白 ING2 蛋白 ING3 蛋白 MEAF4 蛋白 p47ING3 蛋白 P47ING3 蛋白 zgc:56327 蛋白