IMPA1 蛋白
(Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Nov 2009].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| IMPA1 Protein (AA 1-277) (His tag) | 小鼠 | HEK-293 Cells |
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| IMPA1 Protein (AA 1-277) (His tag) | 人 | HEK-293 Cells |
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| IMPA1 Protein (AA 1-277) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| IMPA1 Protein (AA 1-277) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| IMPA1 Protein (AA 1-277) (GST tag) | 人 | 小麦胚 |
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| IMPA1 Protein (AA 1-277) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| IMPA1 Protein (AA 1-277) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| IMPA1 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| IMPA1 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| IMPA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| IMPA1 Protein (Transcript Variant 2) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| IMPA1 Protein (AA 1-277) (His tag) | Orang-Utan | 酵母菌 |
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| IMPA1 Protein (AA 1-270) (His tag) | Mesembryanthemum crystallinum | 酵母菌 |
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| IMPA1 Protein (AA 1-295) (His tag) | Saccharomyces cerevisiae | 酵母菌 |
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| IMPA1 Protein (AA 1-277) (His tag) | 大鼠 | 酵母菌 |
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| IMPA1 Protein (AA 1-285) (His tag) | 非洲爪蟾 | 酵母菌 |
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| IMPA1 Protein (AA 1-277) (His tag) | Pig | 酵母菌 |
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| IMPA1 Protein (AA 1-277) (His tag) | Cow | 酵母菌 |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Orang-Utan
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Mesembryanthemum crystallinum
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Saccharomyces cerevisiae
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 大鼠
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- 非洲爪蟾
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Pig
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- ELISA (ELISA: 所列应用)
- 宿主
- Cow
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Aliases for IMPA1 蛋白
inositol monophosphatase 1 (impa1) 蛋白inositol(myo)-1(or 4)-monophosphatase 1 (impa1) 蛋白
inositol (myo)-1(or 4)-monophosphatase 1 (Impa1) 蛋白
inositol monophosphatase 1 (Impa1) 蛋白
inositol monophosphatase (impa1) 蛋白
inositol monophosphatase 1 (IMPA1) 蛋白
inositol(myo)-1(or 4)-monophosphatase 1 S homeolog (impa1.S) 蛋白
inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1) 蛋白
2610002K09Rik 蛋白
2900059K10Rik 蛋白
AI325909 蛋白
IMP 蛋白
IMPA 蛋白
impa 蛋白
zgc:100926 蛋白
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