IL7R 抗体
(Interleukin 7 Receptor (IL7R))
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008].
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Latest Publications for our IL7R 抗体
: "Influence of glucose and insulin in human adipogenic differentiation models with adipose-derived stem cells." in: Adipocyte, Vol. 8, Issue 1, pp. 254-264, (2019) (PubMed).: "Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques." in: PLoS ONE, Vol. 12, Issue 12, pp. e0188427, (2018) (PubMed).
: "Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006425, (2017) (PubMed).
: "Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+subset." in: Journal of leukocyte biology, Vol. 102, Issue 6, pp. 1289-1298, (2017) (PubMed).
: "DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2861-9, (2015) (PubMed).
: "Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation." in: The Journal of biological chemistry, Vol. 289, Issue 1, pp. 520-8, (2014) (PubMed).
: "IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein." in: PLoS ONE, Vol. 9, Issue 7, pp. e102677, (2014) (PubMed).
: "Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease." in: Blood, Vol. 124, Issue 5, pp. 812-21, (2014) (PubMed).
: "High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer." in: Cancer research, Vol. 74, Issue 8, pp. 2204-16, (2014) (PubMed).
: "An immunological biomarker to predict MTX response in early RA." in: Annals of the rheumatic diseases, Vol. 73, Issue 11, pp. 2047-53, (2014) (PubMed).
Aliases for IL7R 抗体
interleukin 7 receptor (IL7R) 抗体interleukin 7 receptor (Il7r) 抗体
CD127 抗体
CDW127 抗体
IL-7R-alpha 抗体
IL-7RA 抗体
IL-7Ralpha 抗体
IL7R 抗体
IL7RA 抗体
ILRA 抗体
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