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IL6RA 抗体

(Interleukin 6 Receptor, alpha (IL6RA))
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].

24 results

IL6RA 适用: 小鼠 FACS, BP, IF 宿主: 兔 Monoclonal D7715A7D7715A7 unconjugated Recombinant Antibody
产品编号 ABIN7541322
 
IL6RA 适用: 人 WB, Neut 宿主: 小鼠 Monoclonal MM0409-6M30 unconjugated
产品编号 ABIN1983296
 
IL6RA 适用: 小鼠 WB 宿主: 大鼠 Monoclonal RM0114-14F33 unconjugated
产品编号 ABIN1983623
 
IL6RA 适用: 小鼠 ELISA, WB, IC 宿主: 大鼠 Monoclonal 8H129 unconjugated
产品编号 ABIN2289588
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Flow Cytometry (FACS)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • ELISA
    • Western Blotting (WB)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Blocking Peptide (BP)
    • Functional Studies (Func)
    • Immunochromatography (IC)
    • Immunofluorescence (IF)
    • Neutralization (Neut)
    • Surface Plasmon Resonance (SPR)
    • Bio-Layer Interferometry (BLI)
  • 适用
    • Mouse
    • Human
    • Rat
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Rat
    • Goat
    • Human
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • D7715A7D7715A7
    • 8H129
    • APX007
    • MM0409-6M30
    • RM0114-14F33
  • 抗原表位
    • AA 351-460
    • Internal Region
    • AA 20-339
    • AA 20-357
    • AA 20-364
  • 标记
    • 非结合性
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Biotin
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • FITC
    • HRP
    • PE
  • 抗体亚型
    • IgG
    • IgG1
    • IgG2
    • IgG2b
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Recent
  • Supplier
    • antibodies-online
    • Angio-Proteomie
    • USBio

Latest Publications for our IL6RA 抗体

St Leger, Hansen, Karauzum, Horai, Yu, Laurence, Mayer-Barber, Silver, Villasmil, Egwuagu, Datta, Caspi: "STAT-3-independent production of IL-17 by mouse innate-like αβ T cells controls ocular infection." in: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1079-1090, (2019) (PubMed).

Owusu-Boaitey, Bauckman, Zhang, Mysorekar: "Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner." in: Immunity, inflammation and disease, Vol. 4, Issue 4, pp. 413-426, (2018) (PubMed).

Urushima, Fujimoto, Mishima, Ohkawara, Honda, Lee, Kawahata, Serada, Naka: "Leucine-rich alpha 2 glycoprotein promotes Th17 differentiation and collagen-induced arthritis in mice through enhancement of TGF-β-Smad2 signaling in naïve helper T cells." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 137, (2017) (PubMed).

Prystaz, Kaiser, Kovtun, Haffner-Luntzer, Fischer, Rapp, Liedert, Strauss, Waetzig, Rose-John, Ignatius: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." in: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).

Arnold, Boll, Rothaug, Schumacher, Schmidt, Wichert, Schneppenheim, Lokau, Pickhinke, Koudelka, Tholey, Rabe, Scheller, Lucius, Garbers, Rose-John, Becker-Pauly: "Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling." in: Scientific reports, Vol. 7, pp. 44053, (2017) (PubMed).

Wang, Miller, Goswami, Zhang, Ronning, Karlen, Zawadzki, Pugh, Burns: "Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 121, (2017) (PubMed).

Uchibori, Matsuda, Shimodaira, Sugano, Uehara, Honda: "IL-6 trans-signaling is another pathway to upregulate Osteopontin." in: Cytokine, Vol. 90, pp. 88-95, (2016) (PubMed).

Munir, Luu, Clarke, Nash, McGettrick: "Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium." in: PLoS ONE, Vol. 11, Issue 5, pp. e0155161, (2016) (PubMed).

Sommer, Fabri: "Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells." in: PLoS ONE, Vol. 10, Issue 6, pp. e0130395, (2015) (PubMed).

Ke, Zhang, Liu, Liu, Yan, Xu, Bai, Zhu, Lou, Wang, Shi, Jiang, Su, Wang: "Autocrine interleukin-6 drives skin-derived mesenchymal stem cell trafficking via regulating voltage-gated Ca(2+) channels." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 10, pp. 2799-810, (2014) (PubMed).

Aliases for IL6RA 抗体

interleukin 6 receptor (Il6r) 抗体
interleukin 6 receptor (IL6R) 抗体
interleukin 6 receptor, alpha (Il6ra) 抗体
CD126 抗体
gp80 抗体
IL-6R 抗体
IL-6R-1 抗体
IL-6RA 抗体
IL6Q 抗体
Il6r 抗体
IL6R1 抗体
Il6ra 抗体
IL6RA 抗体
IL6RQ 抗体
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