IL27 Receptor alpha 抗体
(Interleukin 27 Receptor, alpha (IL27RA))
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008].
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Latest Publications for our IL27 Receptor alpha 抗体
: "IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations." in: Immunologic research, Vol. 65, Issue 4, pp. 903-912, (2017) (PubMed).: "IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 8, pp. 3008-3017, (2016) (PubMed).
: "The antitumor potential of Interleukin-27 in prostate cancer." in: Oncotarget, Vol. 5, Issue 21, pp. 10332-41, (2015) (PubMed).
: "IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 6, pp. 2634-42, (2014) (PubMed).
: "IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39." in: Nature immunology, Vol. 14, Issue 10, pp. 1054-63, (2013) (PubMed).
: "IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 32, pp. 97, (2013) (PubMed).
: "Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid." in: Journal of biomedical science, Vol. 20, pp. 90, (2013) (PubMed).
: "IL-27-induced gene expression is downregulated in HIV-infected subjects." in: PLoS ONE, Vol. 7, Issue 9, pp. e45706, (2012) (PubMed).
: "Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo." in: Leukemia, Vol. 26, Issue 6, pp. 1365-74, (2012) (PubMed).
: "Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 47, pp. 18502-7, (2007) (PubMed).
Aliases for IL27 Receptor alpha 抗体
interleukin 27 receptor subunit alpha (IL27RA) 抗体interleukin-27 receptor subunit alpha (LOC484907) 抗体
interleukin 27 receptor, alpha (Il27ra) 抗体
interleukin 27 receptor subunit alpha (Il27ra) 抗体
CRL1 抗体
IL-27R 抗体
IL-27RA 抗体
IL27R 抗体
IL27RA 抗体
TCCR 抗体
Tccr 抗体
WSX-1 抗体
WSX1 抗体
Wsx1 抗体
zcytor1 抗体
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