IL21 Receptor 抗体
(Interleukin 21 Receptor (IL21R))
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| IL21 Receptor 抗体 | 人 | 小鼠 Monoclonal |
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| IL21 Receptor 抗体 | 人, 小鼠 | 兔 Polyclonal |
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| IL21 Receptor 抗体 (Biotin) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Latest Publications for our IL21 Receptor 抗体
: "Gene Expression Profile Signature of Aggressive Waldenström Macroglobulinemia with Chromosome 6q Deletion." in: BioMed research international, Vol. 2018, pp. 6728128, (2019) (PubMed).
: "Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer." in: Cells, Vol. 8, Issue 9, (2019) (PubMed).
: "IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 203, Issue 5, pp. 1142-1150, (2019) (PubMed).
: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
: "Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease." in: Cytokine, Vol. 72, Issue 2, pp. 160-5, (2015) (PubMed).
: "IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5139-49, (2015) (PubMed).
: "CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3768-77, (2015) (PubMed).
: "Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity." in: The Journal of experimental medicine, Vol. 209, Issue 3, pp. 581-96, (2012) (PubMed).
: "Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription." in: Immunology, Vol. 132, Issue 4, pp. 540-8, (2011) (PubMed).
: "IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-?-dependent epidermal hyperplasia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 9, pp. 5435-42, (2011) (PubMed).
: "Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer." in: Cells, Vol. 8, Issue 9, (2019) (PubMed).
: "IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 203, Issue 5, pp. 1142-1150, (2019) (PubMed).
: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).
: "Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease." in: Cytokine, Vol. 72, Issue 2, pp. 160-5, (2015) (PubMed).
: "IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 11, pp. 5139-49, (2015) (PubMed).
: "CD4+ T cell-derived IL-21 and deprivation of CD40 signaling favor the in vivo development of granzyme B-expressing regulatory B cells in HIV patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3768-77, (2015) (PubMed).
: "Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity." in: The Journal of experimental medicine, Vol. 209, Issue 3, pp. 581-96, (2012) (PubMed).
: "Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription." in: Immunology, Vol. 132, Issue 4, pp. 540-8, (2011) (PubMed).
: "IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-?-dependent epidermal hyperplasia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 9, pp. 5435-42, (2011) (PubMed).
Aliases for IL21 Receptor 抗体
interleukin 21 receptor (IL21R) 抗体interleukin 21 receptor, tandem duplicate 1 (il21r.1) 抗体
interleukin 21 receptor (Il21r) 抗体
CD360 抗体
il-21ra.a 抗体
IL21R 抗体
NILR 抗体
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