This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin (PMID: 19079364). The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling (PMID: 21663947, 18096367). [provided by RefSeq, Nov 2011].
Quadri, Sarwar, Pinky, Kar, Singh, Mallick, Arava, Nag, Roy, Shariff: "Fluoride induced tissue hypercalcemia, IL-17 mediated inflammation and apoptosis lead to cardiomyopathy: Ultrastructural and biochemical findings." in: Toxicology, Vol. 406-407, pp. 44-57, (2019) (PubMed).
Pekow, Meckel, Dougherty, Huang, Chen, Almoghrabi, Mustafi, Ayaloglu-Butun, Deng, Haider, Hart, Rubin, Kwon, Bissonnette: "miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 17, pp. 5281-5291, (2018) (PubMed).
Miraoui, Dwyer, Sykiotis, Plummer, Chung, Feng, Beenken, Clarke, Pers, Dworzynski, Keefe, Niedziela, Raivio, Crowley, Seminara, Quinton, Hughes, Kumanov, Young, Yialamas, Hall, Van Vliet, Chanoine et al.: "Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism. ..." in: American journal of human genetics, Vol. 92, Issue 5, pp. 725-43, (2013) (PubMed).
Rong, Wang, Li, Ren, Cheng, Li, Wang, Ren, Zhang, Hu, Chang: "IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling." in: Cell research, Vol. 19, Issue 2, pp. 208-15, (2009) (PubMed).
Aliases for IL17RD 抗体
interleukin 17 receptor D (IL17RD) 抗体 interleukin 17 receptor D (il17rd) 抗体 interleukin 17 receptor D (Il17rd) 抗体 2810004A10Rik 抗体 AI428510 抗体 cb208 抗体 HH18 抗体 id:ibd2875 抗体 id:ibd5059 抗体 il-17rd 抗体 IL-17RD 抗体 IL17RD 抗体 il17rlm 抗体 IL17RLM 抗体 RGD1565237 抗体 sef 抗体 SEF 抗体 Sef 抗体 Sef-S 抗体 zgc:136328 抗体