IL15RA 抗体
(Interleukin 15 Receptor, alpha (IL15RA))
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010].
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54 results
IL15RA
适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our IL15RA 抗体
: "NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 202, Issue 6, pp. 1724-1734, (2019) (PubMed).: "Rheumatoid arthritis bone marrow environment supports Th17 response." in: Arthritis research & therapy, Vol. 19, Issue 1, pp. 274, (2018) (PubMed).
: "IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia." in: Cell & bioscience, Vol. 6, pp. 30, (2016) (PubMed).
: "IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness." in: European journal of immunology, Vol. 46, Issue 6, pp. 1371-82, (2016) (PubMed).
: "IL-15 receptor α signaling constrains the development of IL-17-producing γδ T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 31, pp. 9692-7, (2015) (PubMed).
: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).
: "Intramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells." in: Gene therapy, Vol. 22, Issue 1, pp. 76-86, (2015) (PubMed).
: "Anti-inflammatory cytokines directly inhibit innate but not adaptive CD8+ T cell functions." in: Journal of virology, Vol. 88, Issue 13, pp. 7474-84, (2014) (PubMed).
: "Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering. ..." in: Cancer research, Vol. 74, Issue 1, pp. 68-80, (2014) (PubMed).
: "Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia." in: Blood, Vol. 123, Issue 20, pp. 3116-27, (2014) (PubMed).
Aliases for IL15RA 抗体
interleukin 15 receptor subunit alpha (IL15RA) 抗体interleukin 15 receptor subunit alpha (Il15ra) 抗体
interleukin 15 receptor, alpha chain (Il15ra) 抗体
AA690181 抗体
CD215 抗体
IL-15RA 抗体
IL15RA 抗体
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