IL12RB1 抗体
(Interleukin 12 Receptor beta 1 (IL12RB1))
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| IL12RB1 抗体 (AA 284-348) | 小鼠 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (AA 57-488) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (AA 57-458) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 | 人 | 小鼠 Monoclonal |
|
|
|
| IL12RB1 抗体 (APC) | 人 | 小鼠 Monoclonal |
|
|
|
| IL12RB1 抗体 (PE) | 人 | 小鼠 Monoclonal |
|
|
|
| IL12RB1 抗体 (FITC) | 人 | 小鼠 Monoclonal |
|
|
|
| IL12RB1 抗体 (PerCP) | 人 | 小鼠 Monoclonal |
|
|
|
| IL12RB1 抗体 | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Biotin) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (AA 119-280) (FITC) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (AA 119-280) | 人, 大鼠 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Alexa Fluor 647) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
|
|
|
| IL12RB1 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
|
|
|
| Recombinant IL12RB1 抗体 | 人 | 兔 Chimeric |
|
|
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 284-348
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 57-488
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 57-458
Primary Antibody
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 148C09
- 标记
- PerCP
- 抗体亚型
- IgG1, kappa
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 119-280
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 119-280
Primary Antibody
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Chimeric
- 克隆
- 1F11
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG1
Latest Publications for our IL12RB1 抗体
: "Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege." in: PLoS ONE, Vol. 9, Issue 4, pp. e96120, (2014) (PubMed).
: "Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency." in: The Journal of allergy and clinical immunology, Vol. 131, Issue 4, pp. 1146-56, 1156.e1-5, (2013) (PubMed).
: "IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia." in: Blood, Vol. 120, Issue 18, pp. 3774-82, (2012) (PubMed).
: "Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo." in: Leukemia, Vol. 26, Issue 6, pp. 1365-74, (2012) (PubMed).
: "Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans." in: Journal of dermatological science, Vol. 57, Issue 3, pp. 199-206, (2010) (PubMed).
: "Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription." in: Cellular immunology, Vol. 241, Issue 1, pp. 7-13, (2006) (PubMed).
: "A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors." in: Blood, Vol. 104, Issue 7, pp. 2095-101, (2004) (PubMed).
: "IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6221-8, (2000) (PubMed).
: "Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits." in: European journal of immunology, Vol. 29, Issue 6, pp. 2007-13, (1999) (PubMed).
: "Analysis of the multiple interactions between IL-12 and the high affinity IL-12 receptor complex." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 5, pp. 2174-9, (1998) (PubMed).
: "Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency." in: The Journal of allergy and clinical immunology, Vol. 131, Issue 4, pp. 1146-56, 1156.e1-5, (2013) (PubMed).
: "IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia." in: Blood, Vol. 120, Issue 18, pp. 3774-82, (2012) (PubMed).
: "Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo." in: Leukemia, Vol. 26, Issue 6, pp. 1365-74, (2012) (PubMed).
: "Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans." in: Journal of dermatological science, Vol. 57, Issue 3, pp. 199-206, (2010) (PubMed).
: "Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription." in: Cellular immunology, Vol. 241, Issue 1, pp. 7-13, (2006) (PubMed).
: "A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors." in: Blood, Vol. 104, Issue 7, pp. 2095-101, (2004) (PubMed).
: "IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6221-8, (2000) (PubMed).
: "Characterization of mouse interleukin-12 p40 homodimer binding to the interleukin-12 receptor subunits." in: European journal of immunology, Vol. 29, Issue 6, pp. 2007-13, (1999) (PubMed).
: "Analysis of the multiple interactions between IL-12 and the high affinity IL-12 receptor complex." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 5, pp. 2174-9, (1998) (PubMed).
Aliases for IL12RB1 抗体
interleukin 12 receptor subunit beta 1 (Il12rb1) 抗体interleukin 12 receptor subunit beta 1 (IL12RB1) 抗体
interleukin 12 receptor, beta 1 (Il12rb1) 抗体
CD212 抗体
IL-12R 抗体
IL-12R-BETA1 抗体
IL-12R[b] 抗体
Il12rb 抗体
IL12RB 抗体
IL12RB1 抗体
您还需要查找其他产品吗？
You are here:
