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IL12RB1 抗体 (AA 57-458)

IL12RB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886561
发货至: 中国
  • 抗原 See all IL12RB1 抗体
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    抗原表位
    • 16
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 57-458
    适用
    • 41
    • 24
    • 24
    宿主
    • 56
    • 5
    • 2
    克隆类型
    • 59
    • 4
    多克隆
    标记
    • 24
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL12RB1 antibody is un-conjugated
    应用范围
    • 43
    • 13
    • 13
    • 12
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 57 and 458 of Human IL12RB1
    Top Product
    Discover our top product IL12RB1 Primary Antibody
  • 应用备注
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    Biohazard Informations: This product contains thimerosal which is hazardous.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
    Abstract
    IL12RB1 产品
    别名
    Il12rb antibody, IL12RB1 antibody, IL-12R antibody, CD212 antibody, IL-12R-BETA1 antibody, IL12RB antibody, IL-12R[b] antibody, interleukin 12 receptor subunit beta 1 antibody, interleukin 12 receptor, beta 1 antibody, Il12rb1 antibody, IL12RB1 antibody
    背景
    The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily.This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex.This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity.The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections.Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.[provided by RefSeq]
    分子量
    73 kDa
    基因ID
    3594
    NCBI登录号
    NM_005535, NP_005526
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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