电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IL12 蛋白

(Interleukin 12 (IL12))
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].

41 results

IL12 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
产品编号 ABIN7274898
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274899
 
IL12 宿主: 人 宿主: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
产品编号 ABIN2018013
 
IL12 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274908
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN2181328
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN6973104
 
IL12 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, AcA Active
产品编号 ABIN5853918
 
IL12 宿主: 小鼠 宿主: 人细胞 Recombinant > 90 % as determined by SDS-PAGE
产品编号 ABIN7320573
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317148
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7491453
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455632
 
Rockland 010-001-v51-0010 IL12 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant 95,00% SDS
产品编号 ABIN6700020
Rockland Original
Rockland 010-001-v51-0100 IL12 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant 95,00% SDS
产品编号 ABIN6700021
Rockland Original
IL12 宿主: 人 Recombinant BCA
产品编号 ABIN1111712
 
IL12 宿主: 人 宿主: HEK-293T Cells Recombinant > 95 %, as determined by SDS-PAGE Active
产品编号 ABIN1684636
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505604
 
IL12 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7505595
 
IL12 宿主: 大鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
产品编号 ABIN2018061
 
IL12 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7454148
 
IL12 宿主: 人 宿主: CHO Cells Recombinant >98 % (SDS-PAGE)
产品编号 ABIN6253329
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • Activity Assay (AcA)
    • Biochemical Assay (BCA)
    • Flow Cytometry (FACS)
    • Western Blotting (WB)
    • ELISA
    • Immunoprecipitation (IP)
    • Mass Spectrometry (MS)
  • 适用
    • Human
    • Mouse
    • Rat
    • Cynomolgus
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • HEK-293 Cells
    • CHO Cells
    • Human Cells
    • Escherichia coli (E. coli)
    • Insect Cells
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
  • 抗原表位
    • AA 23-328
    • AA 23-215
    • AA 23-335
    • AA 57-253
    • AA 23-219
    • AA 1-335
    • AA 1-219
    • C-Term
    • Extracellular Domain
  • 标记
    • 非结合性
    • His tag
    • Fc Tag
    • Fc-His Tag
    • His tag,AVI tag,DYKDDDDK Tag,Biotin
    • His tag,DYKDDDDK Tag
    • His-Avi Tag
    • His-Avi Tag,Biotin
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Grade
    • Animal-Free
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • Rockland
    • Biospes
    • Cohesion Biosciences
    • ITSI-Biosciences

Latest Publications for our IL12 蛋白

Ling, Gately, Gubler, Stern, Lin, Hollfelder, Su, Pan, Hakimi: "Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 1, pp. 116-27, (1995) (PubMed).

DAndrea, Aste-Amezaga, Valiante, Ma, Kubin, Trinchieri: "Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 1041-8, (1993) (PubMed).

Schoenhaut, Chua, Wolitzky, Quinn, Dwyer, McComas, Familletti, Gately, Gubler: "Cloning and expression of murine IL-12." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 11, pp. 3433-40, (1992) (PubMed).

DAndrea, Rengaraju, Valiante, Chehimi, Kubin, Aste, Chan, Kobayashi, Young, Nickbarg: "Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells." in: The Journal of experimental medicine, Vol. 176, Issue 5, pp. 1387-98, (1992) (PubMed).

Aliases for IL12 蛋白

interleukin 12B (IL12B) 蛋白
interleukin 12A (IL12A) 蛋白
interleukin 12b (Il12b) 蛋白
interleukin 12B (Il12b) 蛋白
interleukin 12a (Il12a) 蛋白
interleukin 12A (Il12a) 蛋白
Interleukin 12 level (IL12) 蛋白
interleukin 12a (il12a) 蛋白
CLMF 蛋白
CLMF2 蛋白
IL-12 蛋白
IL-12 p35 蛋白
Il-12a 蛋白
IL-12B 蛋白
Il-12b 蛋白
IL-12p35 蛋白
Il-12p40 蛋白
IL-12p40 蛋白
Il12 蛋白
IL12B 蛋白
Il12p40 蛋白
IL12p40 蛋白
Ll12a 蛋白
LOC100217488 蛋白
NKSF 蛋白
NKSF2 蛋白
p35 蛋白
p40 蛋白
You are here:
Chat with us!