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IL12 抗体

(Interleukin 12 (IL12))
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].

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  • 抗原: IL12
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN1722430
IL12 抗体 IL12 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 B-T21
  • ELISA (Capture) (ELISA (Capture): 所列应用)
  • ELISPOT (Capture) (ELISpot (Capture): 所列应用)
  • 1 mg
发货至: 中国
ABIN1722431
IL12 抗体 IL12 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 B-P40
  • ELISA (Capture) (ELISA (Capture): 所列应用)
  • 1 mg
发货至: 中国
ABIN1724568
IL12 抗体 IL12 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 B-P24
  • ELISA (ELISA: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • Func (Functional Studies: 所列应用)
  • ELISpot (ELISpot: 所列应用)
  • 500 μg
发货至: 中国
ABIN641215
IL12 抗体 IL12 · Primary Antibody 小鼠 大鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • DB (Dot Blot: 所列应用)
  • ISt (Immunostaining: 所列应用)
  • IA (Immunoassay: 所列应用)
  • CA (Cellular Assay: 所列应用)
  • 200 μg
  • 500 μg
发货至: 中国
ABIN2287553
IL12 抗体 (AA 23-219) (PerCP) IL12 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 9L840
  • FACS (Flow Cytometry: 所列应用)
  • 100 tests
发货至: 中国
ABIN2287631
IL12 抗体 (AA 23-219) (PE) IL12 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 9L841
  • FACS (Flow Cytometry: 所列应用)
  • 100 tests
发货至: 中国
Primary Antibody
  • ELISA (Capture) (ELISA (Capture): 所列应用)
  • ELISPOT (Capture) (ELISpot (Capture): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
B-T21
标记
unconjugated
抗体亚型
IgG1
产品编号 ABIN1722430
Primary Antibody
  • ELISA (Capture) (ELISA (Capture): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
B-P40
标记
unconjugated
抗体亚型
IgG1
产品编号 ABIN1722431
Primary Antibody
  • ELISA (ELISA: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • Func (Functional Studies: 所列应用)
  • ELISpot (ELISpot: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
B-P24
标记
unconjugated
抗体亚型
IgG1
产品编号 ABIN1724568
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • DB (Dot Blot: 所列应用)
  • ISt (Immunostaining: 所列应用)
  • IA (Immunoassay: 所列应用)
  • CA (Cellular Assay: 所列应用)
适用
小鼠
宿主
大鼠
克隆形成能力
Monoclonal
标记
unconjugated
抗体亚型
IgG2b
产品编号 ABIN641215
200 μg (More quantities available)
发货至: 中国
获取报价
Primary Antibody
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
9L840
标记
PerCP
抗体亚型
IgG1
抗原表位
AA 23-219
产品编号 ABIN2287553
Primary Antibody
  • FACS (Flow Cytometry: 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
9L841
标记
PE
抗体亚型
IgG1
抗原表位
AA 23-219
产品编号 ABIN2287631

Latest Publications for our IL12 抗体

Tomasicchio, Semple, Esmail, Meldau, Randall, Pooran, Davids, Cairncross, Anderson, Downs, Malherbe, Novitzky, Panieri, Oelofse, Londt, Naiker, Dheda: "An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells." in: Cancer immunology, immunotherapy : CII, Vol. 68, Issue 1, pp. 71-83, (2019) (PubMed).

Tootoonchian, Pak, Ardekani, Sehati, Abedi-Valugerdi, Kokhaei: "Evaluation of interleukin 12 and CD56+ lymphocyte cells in pediatric hematopoietic stem cell transplantation for early diagnosis of acute graft versus host disease." in: Transplant immunology, Vol. 39, pp. 25-29, (2018) (PubMed).

Ashrafi, Shapouri, Shirkhani, Mahdavi: "Anti-tumor effects of propranolol: Adjuvant activity on a transplanted murine breast cancer model." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 45-51, (2018) (PubMed).

Friedemann, Kalbitzer, Franz, Moeller, Schnabelrauch, Simon, Pompe, Franke: "Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks." in: Advanced healthcare materials, Vol. 6, Issue 7, (2017) (PubMed).

Zheng, Chen, Qu, Chen, Wang, Zhang, Chen: "Influenza H7N9 LAH-HBc virus-like particle vaccine with adjuvant protects mice against homologous and heterologous influenza viruses." in: Vaccine, Vol. 34, Issue 51, pp. 6464-6471, (2017) (PubMed).

Tagawa, Albanese, Bouvet, Moosmann, Mautner, Heissmeyer, Zielinski, Lutter, Hoser, Hastreiter, Hayes, Sugden, Hammerschmidt: "Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing." in: The Journal of experimental medicine, Vol. 213, Issue 10, pp. 2065-80, (2017) (PubMed).

Yazdi, Varastehmoradi, Faghfuri, Mavandadnejad, Mahdavi, Shahverdi: "Adjuvant Effect of Biogenic Selenium Nanoparticles Improves the Immune Responses and Survival of Mice Receiving 4T1 Cell Antigens as Vaccine in Breast Cancer Murine Model." in: Journal of nanoscience and nanotechnology, Vol. 15, Issue 12, pp. 10165-72, (2017) (PubMed).

Breyner, Michon, de Sousa, Vilas Boas, Chain, Azevedo, Langella, Chatel: "Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway." in: Frontiers in microbiology, Vol. 8, pp. 114, (2017) (PubMed).

Lee, Lee, Kim, Kim, Yang, Jeong, Seong: "Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146463, (2016) (PubMed).

Zhang, Morgan, Beane, Zheng, Dudley, Kassim, Nahvi, Ngo, Sherry, Phan, Hughes, Kammula, Feldman, Toomey, Kerkar, Restifo, Yang, Rosenberg: "Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 10, pp. 2278-88, (2016) (PubMed).

Aliases for IL12 抗体

interleukin 12B (IL12B) 抗体
interleukin 12A (IL12A) 抗体
interleukin 12b (Il12b) 抗体
interleukin 12B (Il12b) 抗体
interleukin 12a (Il12a) 抗体
interleukin 12A (Il12a) 抗体
Interleukin 12 level (IL12) 抗体
interleukin 12a (il12a) 抗体
CLMF 抗体
CLMF2 抗体
IL-12 抗体
IL-12 p35 抗体
Il-12a 抗体
IL-12B 抗体
Il-12b 抗体
IL-12p35 抗体
Il-12p40 抗体
IL-12p40 抗体
Il12 抗体
IL12B 抗体
Il12p40 抗体
IL12p40 抗体
Ll12a 抗体
LOC100217488 抗体
NKSF 抗体
NKSF2 抗体
p35 抗体
p40 抗体
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