IL12 抗体
(Interleukin 12 (IL12))
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008].
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Latest Publications for our IL12 抗体
: "An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells." in: Cancer immunology, immunotherapy : CII, Vol. 68, Issue 1, pp. 71-83, (2019) (PubMed).: "Evaluation of interleukin 12 and CD56+ lymphocyte cells in pediatric hematopoietic stem cell transplantation for early diagnosis of acute graft versus host disease." in: Transplant immunology, Vol. 39, pp. 25-29, (2018) (PubMed).
: "Anti-tumor effects of propranolol: Adjuvant activity on a transplanted murine breast cancer model." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 45-51, (2018) (PubMed).
: "Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks." in: Advanced healthcare materials, Vol. 6, Issue 7, (2017) (PubMed).
: "Influenza H7N9 LAH-HBc virus-like particle vaccine with adjuvant protects mice against homologous and heterologous influenza viruses." in: Vaccine, Vol. 34, Issue 51, pp. 6464-6471, (2017) (PubMed).
: "Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing." in: The Journal of experimental medicine, Vol. 213, Issue 10, pp. 2065-80, (2017) (PubMed).
: "Adjuvant Effect of Biogenic Selenium Nanoparticles Improves the Immune Responses and Survival of Mice Receiving 4T1 Cell Antigens as Vaccine in Breast Cancer Murine Model." in: Journal of nanoscience and nanotechnology, Vol. 15, Issue 12, pp. 10165-72, (2017) (PubMed).
: "Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway." in: Frontiers in microbiology, Vol. 8, pp. 114, (2017) (PubMed).
: "Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146463, (2016) (PubMed).
: "Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 10, pp. 2278-88, (2016) (PubMed).
Aliases for IL12 抗体
interleukin 12B (IL12B) 抗体interleukin 12A (IL12A) 抗体
interleukin 12b (Il12b) 抗体
interleukin 12B (Il12b) 抗体
interleukin 12a (Il12a) 抗体
interleukin 12A (Il12a) 抗体
Interleukin 12 level (IL12) 抗体
interleukin 12a (il12a) 抗体
CLMF 抗体
CLMF2 抗体
IL-12 抗体
IL-12 p35 抗体
Il-12a 抗体
IL-12B 抗体
Il-12b 抗体
IL-12p35 抗体
Il-12p40 抗体
IL-12p40 抗体
Il12 抗体
IL12B 抗体
Il12p40 抗体
IL12p40 抗体
Ll12a 抗体
LOC100217488 抗体
NKSF 抗体
NKSF2 抗体
p35 抗体
p40 抗体
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