(Immunoglobulin J Polypeptide, Linker Protein For Immunoglobulin alpha and mu Polypeptides (IGJ))
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Arnold, Wormald, Suter, Radcliffe, Harvey, Dwek, Rudd, Sim: "Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29080-7, (2005) (PubMed).
Aliases for IGJ 抗体
joining chain of multimeric IgA and IgM (Jchain) 抗体 joining chain of multimeric IgA and IgM (JCHAIN) 抗体 immunoglobulin joining chain (Jchain) 抗体 9530090F24Rik 抗体 AI323815 抗体 DKFZp469K0627 抗体 IGCJ 抗体 IGJ 抗体 JCH 抗体 Jch 抗体