(Insulin-Like Growth Factor Binding Protein 3 (IGFBP3))
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Gibson, de Ruijter-Villani, Bauersachs, Stout: "Asynchronous Embryo Transfer Followed by Comparative Transcriptomic Analysis of Conceptus Membranes and Endometrium Identifies Processes Important to the Establishment of Equine Pregnancy." in: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).
Wu, Zhu, Robertson: "Novel nuclear localization and potential function of insulin-like growth factor-1 receptor/insulin receptor hybrid in corneal epithelial cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e42483, (2012) (PubMed).
Aliases for IGFBP3 蛋白
insulin like growth factor binding protein 3 (IGFBP3) 蛋白 insulin-like growth factor binding protein 3 (Igfbp3) 蛋白 insulin-like growth factor binding protein 3 (igfbp3) 蛋白 insulin-like growth factor binding protein 3 (IGFBP-3) 蛋白 insulin-like growth factor binding protein 3 (IGFBP3) 蛋白 insulin-like growth factor binding protein 3 (LOC100305016) 蛋白 insulin like growth factor binding protein 3 (Igfbp3) 蛋白 AI649005 蛋白 BP-53 蛋白 IBP3 蛋白 IGF-BP3 蛋白 IGFBP-3 蛋白 IGFBP3 蛋白 igfbp3 蛋白 IGgfbp3 蛋白 zgc:91788 蛋白