IGF2 蛋白
(Insulin-Like Growth Factor 2 (IGF2))
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
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Latest Publications for our IGF2 蛋白
: "The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis." in: Molecular cancer therapeutics, Vol. 14, Issue 4, pp. 982-93, (2015) (PubMed).: "Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 6, pp. 1947-51, (1988) (PubMed).
: "Tissue-specific expression of insulin-like growth factor II mRNAs with distinct 5' untranslated regions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, Issue 18, pp. 6330-4, (1987) (PubMed).
: "Organization of the human genes for insulin-like growth factors I and II." in: FEBS letters, Vol. 195, Issue 1-2, pp. 179-84, (1986) (PubMed).
: "Insulin-like growth factor II precursor gene organization in relation to insulin gene family." in: Nature, Vol. 310, Issue 5980, pp. 777-81, (1984) (PubMed).
: "Sequence of a cDNA clone encoding human preproinsulin-like growth factor II." in: Nature, Vol. 310, Issue 5980, pp. 775-7, (1984) (PubMed).
Aliases for IGF2 蛋白
insulin like growth factor 2 (IGF2) 蛋白insulin-like growth factor II (LOC100136550) 蛋白
insulin-like growth factor 2a (igf2a) 蛋白
insulin like growth factor 2 S homeolog (igf2.S) 蛋白
insulin-like growth factor 2 (Igf2) 蛋白
insulin-like growth factor 2 (somatomedin A) (IGF2) 蛋白
insulin like growth factor 2 (Igf2) 蛋白
insulin like growth factor 2 L homeolog (igf2.L) 蛋白
AL033362 蛋白
C11orf43 蛋白
igf-2 蛋白
Igf-2 蛋白
IGF-II 蛋白
Igf-II 蛋白
IGF-II-B 蛋白
igf2 蛋白
igf2-a 蛋白
igf2-b 蛋白
igf2b 蛋白
IGFII 蛋白
insigf 蛋白
LOC100136550 蛋白
M6pr 蛋白
Mpr 蛋白
Peg2 蛋白
PP9974 蛋白
pp9974 蛋白
RNIGF2 蛋白
wu:fc26e03 蛋白
zgc:91781 蛋白
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