IDH1 抗体
(Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| IDH1 抗体 (Alexa Fluor 488) | 人, 斑马鱼 | 小鼠 Monoclonal |
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| IDH1 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 405) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 488) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 350) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 555) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Biotin) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 750) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 680) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 647) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (Alexa Fluor 594) | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| IDH1 抗体 | 人, 小鼠, 猴 | 小鼠 Monoclonal |
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| Recombinant IDH1 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| IDH1 抗体 (AA 156-298) | 人, 小鼠, 猴 | 小鼠 Monoclonal |
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| IDH1 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant IDH1 抗体 (AA 281-414) | 人 | 兔 Monoclonal |
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| Recombinant IDH1 抗体 (AA 281-414) | 人 | 兔 Monoclonal |
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| IDH1 抗体 | 人 | 大鼠 Monoclonal |
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| IDH1 抗体 | 人 | 小鼠 Monoclonal |
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| IDH1 抗体 | 人 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 405
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 488
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 350
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 555
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Biotin
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 750
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 680
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 647
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- S05-2G5
- 标记
- Alexa Fluor 594
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人, 小鼠, 猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 156-298
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 质量等级
- Carrier-free
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- IDH1-6806R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- AA 281-414
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- IDH1-6806R
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG, kappa
- 抗原表位
- AA 281-414
Latest Publications for our IDH1 抗体
: "lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma." in: International journal of oncology, Vol. 53, Issue 2, pp. 551-566, (2018) (PubMed).
: "AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis." in: Circulation research, Vol. 120, Issue 1, pp. 99-109, (2016) (PubMed).
: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." in: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
: "DIGE based proteome analysis of mammary gland tissue in water buffalo (Bubalus bubalis): Lactating vis-a-vis heifer." in: Journal of proteomics, Vol. 119C, pp. 100-111, (2015) (PubMed).
: "A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor." in: Cancer discovery, Vol. 4, Issue 7, pp. 828-39, (2014) (PubMed).
: "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27718, (2011) (PubMed).
: "Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value." in: Blood, Vol. 116, Issue 12, pp. 2122-6, (2010) (PubMed).
: "AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis." in: Circulation research, Vol. 120, Issue 1, pp. 99-109, (2016) (PubMed).
: "Identification of proteins responsible for adriamycin resistance in breast cancer cells using proteomics analysis." in: Scientific reports, Vol. 5, pp. 9301, (2016) (PubMed).
: "DIGE based proteome analysis of mammary gland tissue in water buffalo (Bubalus bubalis): Lactating vis-a-vis heifer." in: Journal of proteomics, Vol. 119C, pp. 100-111, (2015) (PubMed).
: "A high-throughput fluorimetric assay for 2-hydroxyglutarate identifies Zaprinast as a glutaminase inhibitor." in: Cancer discovery, Vol. 4, Issue 7, pp. 828-39, (2014) (PubMed).
: "The proteomics of colorectal cancer: identification of a protein signature associated with prognosis." in: PLoS ONE, Vol. 6, Issue 11, pp. e27718, (2011) (PubMed).
: "Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value." in: Blood, Vol. 116, Issue 12, pp. 2122-6, (2010) (PubMed).
Aliases for IDH1 抗体
isocitrate dehydrogenase (NADP(+)) 1, cytosolic (IDH1) 抗体isocitrate dehydrogenase 1 (NADP+), soluble (Idh1) 抗体
isocitrate dehydrogenase (NADP(+)) 1, cytosolic (Idh1) 抗体
isocitrate dehydrogenase 1 (NADP+) L homeolog (idh1.L) 抗体
isocitrate dehydrogenase 1 (NADP+), soluble (idh1) 抗体
isocitrate dehydrogenase 1 (IDH1) 抗体
AI314845 抗体
AI788952 抗体
cb876 抗体
E030024J03Rik 抗体
F23E12.180 抗体
F23E12_180 抗体
fm90e09 抗体
Id-1 抗体
IDCD 抗体
IDH 抗体
Idh-1 抗体
IDH-I 抗体
IDP 抗体
IDPC 抗体
Idpc 抗体
im:7143416 抗体
isocitrate dehydrogenase 1 抗体
isocitrate dehydrogenase I 抗体
NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1 抗体
NADP-CICDH 抗体
PICD 抗体
wu:fm90e09 抗体
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