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HSP90AA2 抗体

(Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2))
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). Plays a key role in slow and fast muscle development in the embryo. Plays a role in myosin expression and assembly.

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  • 抗原: HSP90AA2
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6879343
Recombinant HSP90AA2 抗体 (Biotin) HSP90AA2 · Primary Antibody 人, 大鼠, 小鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN7880984
HSP90AA2 抗体 HSP90AA2 · Primary Antibody 人, 大鼠 兔 Monoclonal 克隆位点 BAC-8
  • WB (Western Blotting: 所列应用)
  • 100 μL
发货至: 中国
ABIN8121910
HSP90AA2 抗体 (pThr5) HSP90AA2 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 50 μL
发货至: 中国
ABIN7875435
HSP90AA2 抗体 (AA 500-700) HSP90AA2 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 HSP90AA1-7247
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 20 μg
发货至: 中国
ABIN7875434
HSP90AA2 抗体 (AA 500-700) HSP90AA2 · Primary Antibody 人 小鼠 Monoclonal 克隆位点 HSP90AA1-7247
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 100 μg
发货至: 中国
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Biotin
蛋白类型
Recombinant Antibody
产品编号 ABIN6879343
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 大鼠
宿主
兔
克隆形成能力
Monoclonal
克隆
BAC-8
标记
unconjugated
抗体亚型
IgG
产品编号 ABIN7880984
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
pThr5
产品编号 ABIN8121910
Primary Antibody
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
HSP90AA1-7247
标记
unconjugated
抗体亚型
IgG1, kappa
抗原表位
AA 500-700
产品编号 ABIN7875435
Primary Antibody
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
质量等级
Carrier-free
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
克隆
HSP90AA1-7247
标记
unconjugated
抗体亚型
IgG1, kappa
抗原表位
AA 500-700
产品编号 ABIN7875434

Latest Publications for our HSP90AA2 抗体

Meng, Chen, Lei, Han, Zhong, Wang, Liu, Gao, Zhang, Tan, Liu, Zhou, Sun, Yang: "Hsp90β promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma." in: Oncogene, (2018) (PubMed).

Deneka, Haber, Kopp, Gaponova, Nikonova, Golemis: "Tumor-targeted SN38 inhibits growth of early stage non-small cell lung cancer (NSCLC) in a KRas/p53 transgenic mouse model." in: PLoS ONE, Vol. 12, Issue 4, pp. e0176747, (2017) (PubMed).

Bzowska, Nogieć, Bania, Zygmunt, Zarębski, Dobrucki, Guzik: "Involvement of cell surface 90 kDa heat shock protein (HSP90) in pattern recognition by human monocyte-derived macrophages." in: Journal of leukocyte biology, Vol. 102, Issue 3, pp. 763-774, (2017) (PubMed).

Ortega, Calvillo, Luna, Pérez-Severiano, Rubio-Osornio, Guevara, Limón: "17-AAG improves cognitive process and increases heat shock protein response in a model lesion with A?25-35." in: Neuropeptides, Vol. 48, Issue 4, pp. 221-32, (2014) (PubMed).

Hunter, OHagan, Kenyon, Dhanani, Prinsloo, Edkins: "Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells." in: PLoS ONE, Vol. 9, Issue 1, pp. e86842, (2014) (PubMed).

Smithline, Nikonova, Hensley, Cai, Egleston, Proia, Seeger-Nukpezah, Golemis: "Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice." in: PLoS ONE, Vol. 9, Issue 12, pp. e114403, (2014) (PubMed).

Ding, Wu, Su, Zhou, Zhao, Deng, Zhang, Liu, Wang, Liu: "Expression of heat shock protein 90 genes during early development and infection in Megalobrama amblycephala and evidence for adaptive evolution in teleost." in: Developmental and comparative immunology, Vol. 41, Issue 4, pp. 683-93, (2013) (PubMed).

Seeger-Nukpezah, Proia, Egleston, Nikonova, Kent, Cai, Hensley, Ying, Chimmanamada, Serebriiskii, Golemis: "Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 31, pp. 12786-91, (2013) (PubMed).

Shelton, Shawgo, Matthews, Lu, Donnelly, Szabla, Tanol, Vielhauer, Rajewski, Matts, Blagg, Robertson: "KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells." in: Molecular pharmacology, Vol. 76, Issue 6, pp. 1314-22, (2009) (PubMed).

De Nardo, Masendycz, Ho, Cross, Fleetwood, Reynolds, Hamilton, Scholz: "A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors." in: The Journal of biological chemistry, Vol. 280, Issue 11, pp. 9813-22, (2005) (PubMed).

Aliases for HSP90AA2 抗体

heat shock protein 90 alpha family class A member 2, pseudogene (HSP90AA2P) 抗体
HSP90ALPHA 抗体
HSPCA 抗体
HSPCAL3 抗体
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