HSD11B1 抗体
(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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55 results
HSD11B1
适用: 人, 大鼠, 小鼠
WB, IHC, ICC, IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
HSD11B1
适用: 人, 大鼠, 小鼠
IP
宿主: 兔
Polyclonal
Magnetic Particles
HSD11B1
适用: 人, 大鼠, 小鼠, Chimpanzee
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
HSD11B1
适用: 人, 大鼠, 小鼠
宿主: 兔
Monoclonal
Alexa Fluor 555
Recombinant Antibody
Latest Publications for our HSD11B1 抗体
: "Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress." in: Science advances, Vol. 5, Issue 9, pp. eaax1978, (2019) (PubMed).: "Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).
: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).
: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).
: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).
: "Induction of 11?-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 192-202, (2013) (PubMed).
: "Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1?-induced COX-2 expression in human term myometrial cells." in: PLoS ONE, Vol. 7, Issue 11, pp. e50167, (2012) (PubMed).
: "Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?" in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 12, pp. 5348-56, (2010) (PubMed).
: "Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 18, pp. 7088-93, (2004) (PubMed).
Aliases for HSD11B1 抗体
hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1) 抗体hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b) 抗体
hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L) 抗体
hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1) 抗体
11-beta-HSD1 抗体
11-DH 抗体
CORTRD2 抗体
HDL 抗体
HSD11 抗体
hsd11 抗体
HSD11B 抗体
hsd11b 抗体
HSD11L 抗体
LRRGT00065 抗体
SDR26C1 抗体
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