Hsc70 蛋白
(Heat Shock 70kDa Protein 8 (HSPA8))
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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19 results
HSPA8
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
HSPA8
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
HSPA8
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % by SDS-PAGE
SDS
1 image
HSPA8
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
>90%
WB, SDS, ELISA, Func, AcA
Active
6 references
HSPA8
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
HSPA8
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
宿主: Cow
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
HSPA8
宿主: 小鸡
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
HSPA8
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % as determined by reducing SDS-PAGE.
HSPA8
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our Hsc70 蛋白
: "Identification of a novel anti‑heat shock cognate 71 kDa protein antibody in patients with Kawasaki disease." in: Molecular medicine reports, Vol. 21, Issue 4, pp. 1771-1778, (2020) (PubMed).: "KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells." in: Molecular pharmacology, Vol. 88, Issue 1, pp. 121-30, (2015) (PubMed).
: "Identification of target antigens of naturally occurring autoantibodies in cerebrospinal fluid." in: Journal of proteomics, (2015) (PubMed).
: "A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane." in: PLoS pathogens, Vol. 11, Issue 8, pp. e1005086, (2015) (PubMed).
: "An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40." in: Nucleic acid therapeutics, Vol. 25, Issue 2, pp. 103-12, (2015) (PubMed).
: "STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity." in: Orphanet journal of rare diseases, Vol. 9, pp. 146, (2014) (PubMed).
: "Discovery of a novel type of autophagy targeting RNA." in: Autophagy, Vol. 9, Issue 3, pp. 403-9, (2013) (PubMed).
: "Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells." in: Cell stress & chaperones, Vol. 15, Issue 5, pp. 545-53, (2010) (PubMed).
: "The formation of intracellular glyceraldehyde-derived advanced glycation end-products and cytotoxicity." in: Journal of gastroenterology, Vol. 45, Issue 6, pp. 646-55, (2010) (PubMed).
: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).
Aliases for Hsc70 蛋白
heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) 蛋白heat shock protein family A (Hsp70) member 8 (HSPA8) 蛋白
heat shock protein family A (Hsp70) member 8 (Hspa8) 蛋白
heat shock 70kDa protein 8 (HSPA8) 蛋白
heat shock protein 8 (Hspa8) 蛋白
heat shock protein 8 (hspa8) 蛋白
2410008N15Rik 蛋白
hsc54 蛋白
HSC54 蛋白
hsc70 蛋白
HSC70 蛋白
Hsc70 蛋白
hsc71 蛋白
HSC71 蛋白
Hsc71 蛋白
Hsc73 蛋白
hsp71 蛋白
HSP71 蛋白
hsp73 蛋白
HSP73 蛋白
Hsp73 蛋白
hspa10 蛋白
HSPA10 蛋白
Hspa10 蛋白
lap1 蛋白
LAP1 蛋白
nip71 蛋白
NIP71 蛋白
wu:fb01g06 蛋白
wu:fi48b06 蛋白
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