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Hydroxyprostaglandin Dehydrogenase 15-(NAD) 产品

(Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

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This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured Hydroxyprostaglandin Dehydrogenase 15-(NAD) Categories

Hydroxyprostaglandin Dehydrogenase 15-(NAD) 抗体

High quality antibodies with extensive validation data.

Hydroxyprostaglandin Dehydrogenase 15-(NAD) ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Hydroxyprostaglandin Dehydrogenase 15-(NAD) 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Hydroxyprostaglandin Dehydrogenase 15-(NAD) 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP
Validations
  • (4)
Cat. No. ABIN516680
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN516675
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7267807
Quantity 100 μL
Datasheet Datasheet

Recommended Hydroxyprostaglandin Dehydrogenase 15-(NAD) ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1118689
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1118686
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4881689
Quantity 96 tests
Datasheet Datasheet

Recommended Hydroxyprostaglandin Dehydrogenase 15-(NAD) 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1307031
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320930
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123382
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Hydroxyprostaglandin Dehydrogenase 15-(NAD) Products

Corwin, Nikolopoulou, Pan, Nunez-Santos, Vallabhajosula, Serrano, Babich, Figueiredo-Pereira: "Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 272, (2018) (PubMed).

Prima, Kaliberova, Kaliberov, Curiel, Kusmartsev: "COX2/mPGES1/PGE2 pathway regulates PD-L1 expression in tumor-associated macrophages and myeloid-derived suppressor cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 5, pp. 1117-1122, (2017) (PubMed).

Yao, Chen, Song, Han, Gandhi, Lim, Wu: "15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury." in: PLoS ONE, Vol. 12, Issue 4, pp. e0176106, (2017) (PubMed).

Wu, Liu, Yang, Liu, Liu, Wang, Xiong, Yu, Huang, Zhuang: "Association of 15-hydroxyprostaglandin dehydrogenate and poor prognosis of obese breast cancer patients." in: Oncotarget, Vol. 8, Issue 14, pp. 22842-22853, (2017) (PubMed).

Mehdawi, Satapathy, Gustafsson, Lundholm, Alvarado-Kristensson, Sjölander: "A potential anti-tumor effect of leukotriene C4 through the induction of 15-hydroxyprostaglandin dehydrogenase expression in colon cancer cells." in: Oncotarget, Vol. 8, Issue 21, pp. 35033-35047, (2017) (PubMed).

Miyagishi, Kosuge, Takano, Endo, Nango, Yamagata-Murayama, Hirose, Kano, Tanaka, Ishige, Ito: "Increased Expression of 15-Hydroxyprostaglandin Dehydrogenase in Spinal Astrocytes During Disease Progression in a Model of Amyotrophic Lateral Sclerosis." in: Cellular and molecular neurobiology, (2016) (PubMed).

Mehdawi, Prasad, Ehrnström, Andersson, Sjölander: "Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells." in: Molecular oncology, Vol. 10, Issue 9, pp. 1415-1429, (2016) (PubMed).

Hu, Li, Maskey, Xu, Peng, Tian, Li, Yang: "15-PGDH expression as a predictive factor response to neoadjuvant chemotherapy in advanced gastric cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6910-8, (2015) (PubMed).

de Hair, Leclerc, Newsum, Maijer, van de Sande, Ramwadhdoebe, van Schaardenburg, van Baarsen, Korotkova, Gerlag, Tak, Jakobsson: "Expression of Prostaglandin E2 Enzymes in the Synovium of Arthralgia Patients at Risk of Developing Rheumatoid Arthritis and in Early Arthritis Patients." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133669, (2015) (PubMed).

Hsiao, Thatcher, Colas, Serhan, Phipps, Sime: "Resolvin D1 Reduces Emphysema and Chronic Inflammation." in: The American journal of pathology, Vol. 185, Issue 12, pp. 3189-201, (2015) (PubMed).

Synonyms and alternative names related to Hydroxyprostaglandin Dehydrogenase 15-(NAD)

carbonyl reductase 1 (CBR1), 15-hydroxyprostaglandin dehydrogenase (HPGD), hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), 15-hydroxyprostaglandin dehydrogenase L homeolog (hpgd.L), 15-hydroxyprostaglandin dehydrogenase (hpgd), 15-hydroxyprostaglandin dehydrogenase (pgdh), hydroxyprostaglandin dehydrogenase 15 (NAD) (Hpgd), 15-hydroxyprostaglandin dehydrogenase (Hpgd), 15-hydroxyprostaglandin dehydrogenase (PTRG_03214), 15-hydroxyprostaglandin dehydrogenase (VDBG_09957), 15-PGDH, AV026552, CBR, hCBR1, MGC79454, MGC80546, PGDH, PGDH1, PHOAR1, SDR21C1, SDR36C1

Protein level used designations for Hydroxyprostaglandin Dehydrogenase 15-(NAD)

  • 15-hydroxyprostaglandin dehydrogenase
  • NADPH-dependent carbonyl reductase 1
  • carbonyl reductase (NADPH) 1
  • carbonyl reductase [NADPH] 1
  • prostaglandin 9-ketoreductase
  • prostaglandin-E(2) 9-reductase
  • short chain dehydrogenase/reductase family 21C, member 1
  • 15-hydroxyprostaglandin dehydrogenase [NAD(+)]
  • NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
  • prostaglandin dehydrogenase 1
  • short chain dehydrogenase/reductase family 36C, member 1
  • hydroxyprostaglandin dehydrogenase 15-(NAD)
  • 15-PGDH
  • NAD+ dependent 15-hydroxyprostaglandin dehydrogenase
  • PGDH
  • NAD-dependent 15-hydroxyprostaglandin dehydrogenase
  • 15-hydroxyprostaglandin dehydrogenase (NAD+)
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