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HLA-DRB1 蛋白

(Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].

8 results :

HLA-DRB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % by SDS - PAGE SDS
产品编号 ABIN5853579
 
HLA-DRB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant SDS, WB, ELISA
产品编号 ABIN7577422
 
HLA-DRB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC
产品编号 ABIN7412935
 
HLA-DRB1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % SDS, WB, Imm, PC
产品编号 ABIN7412938
 
HLA-DRB1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85% by SDS-PAGE SDS
产品编号 ABIN6388240
 
HLA-DRB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % pure SDS
产品编号 ABIN2129737
 
HLA-DRB1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2722844
 
HLA-DRB1 宿主: 犬 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1660811
 
  • 类型 Protein
    • Protein
  • 应用范围
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Antibody Production (AbP)
    • Standard (STD)
  • 适用
    • Human
    • Dog
    • Mouse
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • Baculovirus infected Insect Cells
    • HEK-293 Cells
    • Yeast
  • 抗原表位
    • AA 30-227
    • AA 27-264
    • AA 30-266
  • 标记
    • His tag
    • Myc-DYKDDDDK Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • CUSABIO
    • OriGene

Aliases for HLA-DRB1 蛋白

major histocompatibility complex, class II, DR beta 1 (hla-drb1) 蛋白
major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) 蛋白
DRB1 蛋白
DRw10 蛋白
HLA-DR1B 蛋白
HLA-DRB 蛋白
MGC108235 蛋白
SS1 蛋白
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