HLA-DQA2 抗体
(Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010].
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Latest Publications for our HLA-DQA2 抗体
: "Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy." in: Nature genetics, Vol. 42, Issue 9, pp. 786-9, (2010) (PubMed).: "Genome-wide association study in alopecia areata implicates both innate and adaptive immunity." in: Nature, Vol. 466, Issue 7302, pp. 113-7, (2010) (PubMed).
: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, (2010) (PubMed).
: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
Aliases for HLA-DQA2 抗体
major histocompatibility complex, class II, DQ alpha 2 (HLA-DQA2) 抗体DX-ALPHA 抗体
HLA-DXA 抗体
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