High Mobility Group AT-Hook 1 抗体
(High Mobility Group AT-Hook 1 (HMGA1))
This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our High Mobility Group AT-Hook 1 抗体
: "Extranuclear Translocation of High-Mobility Group A1 Reduces the Invasion of Extravillous Trophoblasts Involved in the Pathogenesis of Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697250, (2017) (PubMed).: "Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1." in: International journal of oncology, Vol. 46, Issue 6, pp. 2526-34, (2015) (PubMed).
: "Knockdown of HMGA1 inhibits human breast cancer cell growth and metastasis in immunodeficient mice." in: Biochemical and biophysical research communications, Vol. 434, Issue 1, pp. 70-4, (2013) (PubMed).
: "Differential expression and prognostic value of HMGA1 in pancreatic head and periampullary cancer." in: European journal of cancer (Oxford, England : 1990), Vol. 46, Issue 18, pp. 3393-9, (2010) (PubMed).
: "High mobility group AT-hook 1 (HMGA1) is an independent prognostic factor and novel therapeutic target in pancreatic adenocarcinoma." in: Cancer, Vol. 113, Issue 2, pp. 302-14, (2008) (PubMed).
: "HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 22, pp. 7637-44, (2004) (PubMed).
Aliases for High Mobility Group AT-Hook 1 抗体
high mobility group AT-hook 1 (HMGA1) 抗体high mobility group AT-hook 1 (Hmga1) 抗体
high mobility group protein HMG-I/HMG-Y (TSC_c24220) 抗体
high mobility group AT-hook 1a (hmga1a) 抗体
high mobility group protein HMG-I/HMG-Y (LOC705105) 抗体
high mobility group AT-hook 1b (hmga1b) 抗体
AL023995 抗体
HMG-I(Y) 抗体
HMG-R 抗体
HMG-Y 抗体
hmga1 抗体
HMGA1 抗体
HMGA1A 抗体
Hmga1a 抗体
Hmga1b 抗体
Hmgi 抗体
HMGIY 抗体
Hmgiy 抗体
hmgiy 抗体
Hmgy 抗体
wu:fb12b06 抗体
wu:fb18f11 抗体
wu:fc19f01 抗体
wu:fi38b05 抗体
zgc:85677 抗体
zgc:153948 抗体
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