Hepcidin 25 产品
(Hepcidin 25 (HEPC25))
Categories
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
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Featured Hepcidin 25 Categories
Hepcidin 25 抗体
High quality antibodies with extensive validation data.
Hepcidin 25 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended Hepcidin 25 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IF (p), WB, IF (cc), IHC (p), ELISA, IHC (fro)
Validations
Cat. No.
ABIN2175579
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IF (p), IHC (p)
Validations
Cat. No.
ABIN1715141
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), ELISA, IHC (fro)
Validations
Cat. No.
ABIN2175584
Quantity
100 μL
Datasheet
Datasheet
Recommended Hepcidin 25 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967374
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967372
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6967373
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our Hepcidin 25 Products
: "C-reactive protein but not hepcidin, NGAL and transferrin determines the ESA resistance in hemodialysis patients." in: Renal failure, Vol. 38, Issue 1, pp. 89-95, (2017) (PubMed).: "Serum hepcidin concentrations correlate with ferritin in patients with inflammatory bowel disease." in: Journal of Crohn's & colitis, Vol. 8, Issue 11, pp. 1392-7, (2015) (PubMed).
: "A novel splicing mutation of TMPRSS6 in a Chinese child with iron-refractory iron deficiency anaemia." in: British journal of haematology, (2015) (PubMed).
Synonyms and alternative names related to Hepcidin 25
hepcidin antimicrobial peptide (HAMP), HEPC, HFE2B, LEAP1, PLTRProtein level used designations for Hepcidin 25
- hepcidin
- liver-expressed antimicrobial peptide 1
- putative liver tumor regressor
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