Hepatitis B Virus Core Antigen 产品
(Hepatitis B Virus Core Antigen (HBcAg))
Categories
Self assembles to form an icosahedral capsid. Most capsid appear to be large particles with a icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins. Entering capsid are transported along microtubules to the nucleus. Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta. Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153. Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm. Immature capsids get stucked in the basket. Capsids encapsulate the pre-genomic RNA and the P protein. Pre- genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm. The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions. {ECO:0000255|HAMAP-Rule:MF_04076}. Encapsidates hepatitis delta genome. {ECO:0000255|HAMAP- Rule:MF_04076}.
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Featured Hepatitis B Virus Core Antigen Categories
Hepatitis B Virus Core Antigen 抗体
High quality antibodies with extensive validation data.
Hepatitis B Virus Core Antigen 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Hepatitis B Virus Core Antigen 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Hepatitis B Virus (HBV), Virus
Application
ELISA, IHC (p), IF (p)
Validations
- (1)
Cat. No.
ABIN722991
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Hepatitis B Virus (HBV), Virus
Application
ELISA, IHC (p)
Validations
Cat. No.
ABIN722993
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Hepatitis B Virus (HBV), Virus
Application
IF (p)
Validations
Cat. No.
ABIN5004261
Quantity
100 μL
Datasheet
Datasheet
Recommended Hepatitis B Virus Core Antigen ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Qualitative Sandwich ELISA
Validations
Cat. No.
ABIN5025326
Quantity
96 tests
Datasheet
Datasheet
Recommended Hepatitis B Virus Core Antigen 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Hepatitis B Virus (HBV)
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7478071
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Hepatitis B Virus (HBV)
Source
Yeast (Pichia pastoris)
Validations
Cat. No.
ABIN7478072
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Hepatitis B Virus (HBV)
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN5569544
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Hepatitis B Virus Core Antigen Products
: "Immunization with lentiviral vector‑modified dendritic cells encoding ubiquitinated hepatitis B core antigen promotes Th1 differentiation and antiviral immunity by enhancing p38 MAPK and JNK ..." in: Molecular medicine reports, Vol. 18, Issue 5, pp. 4691-4699, (2019) (PubMed).: "Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model." in: ACS infectious diseases, (2018) (PubMed).
: "Hepatitis B virus core antigen binds and activates naive human B cells in vivo: studies with a human PBL-NOD/SCID mouse model." in: Journal of virology, Vol. 75, Issue 14, pp. 6359-66, (2001) (PubMed).
Synonyms and alternative names related to Hepatitis B Virus Core Antigen
precore; HBe antigen; PreC; HBeAg; precore protein; external core antigen; HBeAg; p25 (C)Protein level used designations for Hepatitis B Virus Core Antigen
- C0 uORF
- Core antigen
- Core protein
- HBcAg
- HBe antigen
- HBeAg
- PreC
- capsid protein
- external core antigen
- p21.5
- p25
- pre-capsid protein
- precore
- precore protein
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