HDAC4 蛋白
(Histone Deacetylase 4 (HDAC4))
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
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13 results
HDAC4
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
HDAC4
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
HDAC4
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
WB, SDS, PC, Imm
custom-made
HDAC4
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
HDAC4
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
HDAC4
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
EAA
Active
1 image
HDAC4
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS
1 image
Latest Publications for our HDAC4 蛋白
: "PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).
Aliases for HDAC4 蛋白
histone deacetylase 4 (PTRG_03699) 蛋白hypothetical protein (PGTG_15512) 蛋白
Histone deacetylase 4 (HDAC4) 蛋白
GF18710 gene product from transcript GF18710-RC (Dana\GF18710) 蛋白
histone deacetylase 4 (HDAC4) 蛋白
histone deacetylase 4 (Hdac4) 蛋白
histone deacetylase 4 (hdac4) 蛋白
4932408F19Rik 蛋白
AHO3 蛋白
AI047285 蛋白
BDMR 蛋白
CG1770 蛋白
DanaGF18710 蛋白
dana_GLEANR_19966 蛋白
DHDAC4 蛋白
dHDAC4 蛋白
Dmel\\CG1770 蛋白
dmHDA405 蛋白
GC1770 蛋白
GF18710 蛋白
HA6116 蛋白
HD4 蛋白
HDAC 蛋白
HDAC-4 蛋白
HDAC-A 蛋白
hdac4 蛋白
HDAC4 蛋白
HDAC4a 蛋白
HDACA 蛋白
wu:fa96d08 蛋白
wu:fc56f08 蛋白
zgc:152701 蛋白
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