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GREM1 蛋白

(Gremlin 1 (GREM1))
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

26 results

GREM1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB, ELISA Active
产品编号 ABIN5608259
 
GREM1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) > 90 % AcA, CC Active
产品编号 ABIN6238120
 
GREM1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7584561
 
GREM1 宿主: 非洲爪蟾 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1511647
 
GREM1 宿主: 猕猴 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1640173
 
GREM1 宿主: 小鸡 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1459332
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Functional Studies (Func)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Cell Culture (CC)
    • Antibody Production (AbP)
    • Immunoprecipitation (IP)
    • Protein Interaction (PI)
    • Standard (STD)
  • 适用
    • Human
    • Rat
    • Chicken
    • Mouse
    • Rhesus Monkey
    • Xenopus laevis
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • CHO Cells
    • Wheat germ
    • Mammalian Cells
  • 抗原表位
    • AA 25-184
    • AA 26-184
    • partial
    • AA 1-184
    • AA 25-124
    • AA 25-182
    • AA 27-184
    • Transcript Variant 1
  • 标记
    • His tag
    • 非结合性
    • Fc Tag
    • GST tag
    • His-IF2DI Tag
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • 生物活性
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • Abbexa
    • ProSci
    • ACROBiosystems
    • Cloud-Clone
    • OriGene

Latest Publications for our GREM1 蛋白

Kim, Sung, Youn, Park: "Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells." in: Biochemical and biophysical research communications, Vol. 533, Issue 4, pp. 1378-1384, (2020) (PubMed).

Aliases for GREM1 蛋白

gremlin 1a, DAN family BMP antagonist (grem1a) 蛋白
gremlin 1, DAN family BMP antagonist (GREM1) 蛋白
gremlin 1 (LOC662541) 蛋白
gremlin 1, DAN family BMP antagonist (grem1) 蛋白
gremlin 1, DAN family BMP antagonist (Grem1) 蛋白
gremlin 1, DAN family BMP antagonist L homeolog (grem1.L) 蛋白
Cktsf1b1 蛋白
CKTSF1B1 蛋白
cktsf1b1 蛋白
dand2 蛋白
DAND2 蛋白
drm 蛋白
Drm 蛋白
DRM 蛋白
Grem 蛋白
grem1 蛋白
GREM1 蛋白
gremlin 蛋白
GREMLIN 蛋白
gremlin-1 蛋白
ihg-2 蛋白
IHG-2 蛋白
ld 蛋白
MGC136702 蛋白
pig2 蛋白
zgc:136702 蛋白
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