GREM1 抗体
(Gremlin 1 (GREM1))
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
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95 results
GREM1
适用: 人
IHC, ELISA
宿主: Human
Monoclonal
1D9
unconjugated
Recombinant Antibody
Latest Publications for our GREM1 抗体
: "Gremlin is a key pro-fibrogenic factor in chronic pancreatitis." in: Journal of molecular medicine (Berlin, Germany), (2015) (PubMed).: "Tubular overexpression of gremlin induces renal damage susceptibility in mice." in: PLoS ONE, Vol. 9, Issue 7, pp. e101879, (2014) (PubMed).
: "Overexpression of Gremlin-1 in patients with Loeys-Dietz syndrome: implications on pathophysiology and early disease detection." in: PLoS ONE, Vol. 9, Issue 8, pp. e104742, (2014) (PubMed).
: "Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma." in: Oncology reports, Vol. 30, Issue 2, pp. 968-78, (2013) (PubMed).
: "Molecular differentiation between osteophytic and articular cartilage--clues for a transient and permanent chondrocyte phenotype." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 20, Issue 2, pp. 162-71, (2012) (PubMed).
: "Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 24, Issue 4, pp. 1121-9, (2009) (PubMed).
: "Elevated levels of gremlin-1 in eutopic endometrium and peripheral serum in patients with endometriosis." in: Fertility and sterility, Vol. 91, Issue 2, pp. 350-8, (2009) (PubMed).
: "Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy." in: Transplantation proceedings, Vol. 40, Issue 3, pp. 734-9, (2008) (PubMed).
: "A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 11, pp. 1204-14, (2008) (PubMed).
: "Thy-1 is expressed in myofibroblasts but not found in hepatic stellate cells following liver injury." in: Histochemistry and cell biology, Vol. 131, Issue 1, pp. 115-27, (2008) (PubMed).
Aliases for GREM1 抗体
gremlin 1a, DAN family BMP antagonist (grem1a) 抗体gremlin 1, DAN family BMP antagonist (GREM1) 抗体
gremlin 1 (LOC662541) 抗体
gremlin 1, DAN family BMP antagonist (grem1) 抗体
gremlin 1, DAN family BMP antagonist (Grem1) 抗体
gremlin 1, DAN family BMP antagonist L homeolog (grem1.L) 抗体
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