GPR56 抗体
(G Protein-Coupled Receptor 56 (GPR56))
This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Latest Publications for our GPR56 抗体
: "Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 19, pp. 6194-9, (2015) (PubMed).: "GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2." in: Cancer research, Vol. 74, Issue 4, pp. 1022-31, (2014) (PubMed).
: "The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity." in: The Journal of biological chemistry, Vol. 286, Issue 33, pp. 28914-21, (2011) (PubMed).
Aliases for GPR56 抗体
adhesion G protein-coupled receptor G1 (ADGRG1) 抗体adhesion G protein-coupled receptor G1 (adgrg1) 抗体
adhesion G protein-coupled receptor G1 (Adgrg1) 抗体
G protein-coupled receptor 56 (GPR56) 抗体
BFPP 抗体
Cyt28 抗体
fc49b10 抗体
GPR56 抗体
TM7LN4 抗体
TM7XN1 抗体
wu:fc49b10 抗体
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