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Glucocorticoid Receptor beta 产品

(Glucocorticoid Receptor beta (NR3C1))
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

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Featured Glucocorticoid Receptor beta Categories

Glucocorticoid Receptor beta 抗体

High quality antibodies with extensive validation data.

Glucocorticoid Receptor beta ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended Glucocorticoid Receptor beta 抗体

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Cat. No.
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Application WB, IHC (p), IP, IHC
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Cat. No. ABIN2741122
Quantity 50 μL
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Application WB, IHC (p), ELISA, FACS, ICC, IF (cc), IF (p), IHC (fro)
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Cat. No. ABIN1714189
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Reactivity Human
Application WB, IP, IHC (fp)
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Recommended Glucocorticoid Receptor beta ELISA试剂盒

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Reactivity
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Reactivity Human
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Cat. No. ABIN6956114
Quantity 96 tests
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6967026
Quantity 96 tests
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Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6967027
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Recommended Glucocorticoid Receptor beta 蛋白

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Reactivity
Source
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Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422652
Quantity 100 μg
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Latest Publications for our Glucocorticoid Receptor beta Products

Kok, van den Hoogen, van Roon, Adriaansen, Fritsch-Stork, Nguyen, Goldschmeding, Radstake, Bovenschen: "Systemic and local granzyme B levels are associated with disease activity, kidney damage and interferon signature in systemic lupus erythematosus." in: Rheumatology (Oxford, England), Vol. 56, Issue 12, pp. 2129-2134, (2017) (PubMed).

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