GLS2 产品
(Glutaminase 2 (Liver, Mitochondrial) (GLS2))
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The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq, Jul 2008].
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Featured GLS2 Categories
GLS2 抗体
High quality antibodies with extensive validation data.
GLS2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GLS2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GLS2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (6)
Cat. No.
ABIN7436594
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN6243842
Quantity
200 μL
Datasheet
Datasheet
Recommended GLS2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956184
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1134923
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1134924
Quantity
96 tests
Datasheet
Datasheet
Recommended GLS2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355246
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3080858
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3122411
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GLS2 Products
: "18F-labeled magnetic nanoparticles for monitoring anti-angiogenic therapeutic effects in breast cancer xenografts." in: Journal of nanobiotechnology, Vol. 17, Issue 1, pp. 105, (2019) (PubMed).: "MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 21, pp. 6539-44, (2015) (PubMed).
: "Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer." in: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 890-901, (2014) (PubMed).
: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
: "Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism." in: Molecular autism, Vol. 4, Issue 1, pp. 6, (2013) (PubMed).
: "Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1387-96, (2012) (PubMed).
: "Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer." in: Scientific reports, Vol. 7, Issue 1, pp. 16159 (PubMed).
Synonyms and alternative names related to GLS2
glutaminase 2 (glsA2), glutaminase 2 (LOAG_03311), glutaminase 2a (liver, mitochondrial) (gls2a), glutaminase 2 (GLS2), glutaminase 2 (liver, mitochondrial) (Gls2), glutaminase 2 (Gls2), A330074B06Rik, AI195532, GA, Ga, GLS, hLGA, LGA, Lga, si:ch211-216k22.10Protein level used designations for GLS2
- glutaminase 2
- L-glutamine amidohydrolase
- breast cell glutaminase
- glutaminase I
- glutaminase liver isoform, mitochondrial
- phosphate-activated glutaminase
- phosphate-dependent glutaminase
- L-glutaminase
- liver mitochondrial glutaminase
- GLS
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