This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008].
Shubbar, Helou, Kovács, Nemes, Hajizadeh, Enerbäck, Einbeigi: "High levels of γ-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer." in: BMC cancer, Vol. 13, pp. 47, (2013) (PubMed).