The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Wang, Guo, Wang, Liu, Zhang, Cui, Wu: "Downregulation of microRNA-483-5p Promotes Cell Proliferation and Invasion by Targeting GFRA4 in Hirschsprung's Disease." in: DNA and cell biology, Vol. 36, Issue 11, pp. 930-937, (2017) (PubMed).
Aliases for GFRA4 抗体
GDNF family receptor alpha 4 (GFRA4) 抗体 GDNF family receptor alpha 4a (gfra4a) 抗体 GDNF family receptor alpha 4 (Gfra4) 抗体 glial cell line derived neurotrophic factor family receptor alpha 4 (Gfra4) 抗体 AW060733 抗体 G630015H18Rik 抗体 zgc:171814 抗体