Geminin 抗体
(Geminin, DNA Replication Inhibitor (GMNN))
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011].
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72 results
GMNN
适用: 人
WB, IHC, ELISA
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our Geminin 抗体
: "Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis." in: Nature communications, Vol. 4, pp. 1885, (2013) (PubMed).: "Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex." in: Nature cell biology, Vol. 15, Issue 7, pp. 797-806, (2013) (PubMed).
: "Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation." in: Molecular and cellular biology, Vol. 29, Issue 10, pp. 2609-21, (2009) (PubMed).
: "The regulation of embryonic patterning and DNA replication by geminin." in: Cellular and molecular life sciences : CMLS, Vol. 62, Issue 13, pp. 1425-33, (2005) (PubMed).
: "The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions." in: Nature, Vol. 427, Issue 6976, pp. 749-53, (2004) (PubMed).
: "Increased expression of geminin stimulates the growth of mammary epithelial cells and is a frequent event in human tumors." in: Journal of cellular physiology, Vol. 202, Issue 1, pp. 215-22, (2004) (PubMed).
: "Identification of BRCA1-IRIS, a BRCA1 locus product." in: Nature cell biology, Vol. 6, Issue 10, pp. 954-67, (2004) (PubMed).
: "DNA replication licensing in somatic and germ cells." in: Journal of cell science, Vol. 117, Issue Pt 24, pp. 5875-86, (2004) (PubMed).
: "Inhibition of eukaryotic DNA replication by geminin binding to Cdt1." in: Science (New York, N.Y.), Vol. 290, Issue 5500, pp. 2309-12, (2000) (PubMed).
Aliases for Geminin 抗体
geminin, DNA replication inhibitor (GMNN) 抗体CG3183 gene product from transcript CG3183-RA (geminin) 抗体
geminin, DNA replication inhibitor (gmnn) 抗体
geminin (LOC410093) 抗体
GE24654 gene product from transcript GE24654-RA (Dyak\geminin) 抗体
geminin (Gmnn) 抗体
geminin, DNA replication inhibitor (Gmnn) 抗体
anon-WO0257455.1 抗体
AW546347 抗体
CG3183 抗体
Dmel\\CG3183 抗体
Dm Geminin 抗体
Dm geminin 抗体
DyakGE24654 抗体
dyak_GLEANR_833 抗体
GB16871 抗体
GE24654 抗体
Gem 抗体
gem 抗体
Geminin 抗体
geminin 抗体
GMNN 抗体
l(2)k14019 抗体
LOC100049517 抗体
sb:cb254 抗体
v(2)k09107 抗体
zgc:66217 抗体
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