(Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))
The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012].
Bardy, van den Hurk, Kakaradov, Erwin, Jaeger, Hernandez, Eames, Paucar, Gorris, Marchand, Jappelli, Barron, Bryant, Kellogg, Lasken, Rutten, Steinbusch, Yeo, Gage: "Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology." in: Molecular psychiatry, Vol. 21, Issue 11, pp. 1573-1588, (2016) (PubMed).
Aliases for GDAP1L1 抗体
ganglioside induced differentiation associated protein 1 like 1 (GDAP1L1) 抗体 ganglioside induced differentiation associated protein 1-like 1 (gdap1l1) 抗体 ganglioside induced differentiation associated protein 1 like 1 (gdap1l1) 抗体 ganglioside-induced differentiation-associated protein 1-like 1 (Gdap1l1) 抗体 dJ881L22.1 抗体 dJ995J12.1.1 抗体 Gdap1l 抗体 GDAP1L1 抗体 MGC146673 抗体