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GCH1 蛋白

(GTP Cyclohydrolase 1 (GCH1))
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described\; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008].

10 results :

custom-made GCH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7547848
 
GCH1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Pubmed 1 reference
产品编号 ABIN1354910
 
GCH1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 97 % WB, PC, SDS, Imm
产品编号 ABIN7422661
 
custom-made GCH1 宿主: 人 宿主: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
产品编号 ABIN3080453
 
GCH1 宿主: 人, 大鼠, 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, PC
产品编号 ABIN2750202
 
GCH1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN7584429
 
GCH1 宿主: Velvet bean (Mucuna pruriens) 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1608968
 
GCH1 宿主: Euglena gracilis 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1461743
 
GCH1 宿主: Rainbow Trout 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1608986
 
GCH1 宿主: 小鸡 宿主: 酵母菌 Recombinant > 90 % ELISA
产品编号 ABIN1459043
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • Positive Control (PC)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
  • 适用
    • Human
    • Rat
    • Chicken
    • Euglena gracilis
    • Mouse
    • Rainbow Trout
    • Velvet bean (Mucuna pruriens)
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Yeast
    • Escherichia coli (E. coli)
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-250
    • AA 1-80
    • AA 1-225
    • AA 1-236
    • AA 12-241
    • AA 16-250
  • 标记
    • His tag
    • GST tag
    • Strep Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Grade
    • custom-made
  • Supplier
    • CUSABIO
    • antibodies-online
    • FabGennix

Latest Publications for our GCH1 蛋白

Widder, Chen, Li, Dikalov, Thöny, Hatakeyama, Harrison: "Regulation of tetrahydrobiopterin biosynthesis by shear stress." in: Circulation research, Vol. 101, Issue 8, pp. 830-8, (2007) (PubMed).

Aliases for GCH1 蛋白

GTP cyclohydrolase 1 (GCH1) 蛋白
GTP cyclohydrolase 1 (Gch1) 蛋白
GTP cyclohydrolase 1 (gch1) 蛋白
GTP cyclohydrolase 1 (Weevi_1190) 蛋白
GTP cyclohydrolase 1 (Halhy_0838) 蛋白
GTP cyclohydrolase 1 (Sinme_1220) 蛋白
GTP cyclohydrolase 1 (Sphch_1077) 蛋白
GTP cyclohydrolase 1-like (LOC100136794) 蛋白
DYT5 蛋白
DYT5a 蛋白
DYT14 蛋白
GCH 蛋白
Gch 蛋白
gch1a 蛋白
GTP-CH 蛋白
GTP-CH-1 蛋白
GTPCH 蛋白
GTPCH1 蛋白
HPABH4B 蛋白
MGC89622 蛋白
wu:fc16b10 蛋白
zgc:195269 蛋白
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