This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Latest Publications for our Gastrin-Releasing Peptide ELISA试剂盒
Yamada, Ueda, Nakamura, Kanayama, Tamura, Hashimoto, Matsumoto, Ishii: "Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice." in: Experimental dermatology, (2017) (PubMed).
Kamata, Kimura, Matsuda, Tengara, Kamo, Umehara, Iizumi, Kawasaki, Suga, Ogawa, Tominaga, Takamori: "Relationships among plasma granzyme B level, pruritus and dermatitis in patients with atopic dermatitis." in: Journal of dermatological science, Vol. 84, Issue 3, pp. 266-271, (2016) (PubMed).
Yang, Wu, Wei, Dou, Zhao, Wang, Bian, Tong, Xia, Xia, Dai: "Oral curcumin has anti-arthritic efficacy through somatostatin generation via cAMP/PKA and Ca(2+)/CaMKII signaling pathways in the small intestine." in: Pharmacological research, Vol. 95-96, pp. 71-81, (2015) (PubMed).