GALR2 产品
(Galanin Receptor 2 (GALR2))
Categories
Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008].
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Featured GALR2 Categories
Recommended GALR2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
- (3)
Cat. No.
ABIN1386167
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1048645
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (2)
Cat. No.
ABIN2854711
Quantity
100 μL
Datasheet
Datasheet
Recommended GALR2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3110128
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3132242
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3080657
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GALR2 Products
: "Elevated expression of galanin receptors in childhood neuroblastic tumors." in: Neuroendocrinology, Vol. 75, Issue 2, pp. 130-8, (2002) (PubMed).Synonyms and alternative names related to GALR2
galanin receptor 2 (GALR2), galanin receptor 2 (Galr2), galanin receptor 2 (LOC100037698), transcription regulator. LacI family, raffinose related (rafR), DNA-binding transcriptional regulator GalR (galR2), galactose operon repressor (galR2), galanin receptor type 2 (LOC103690156), GAL2-R, GALNR2, GALR-2, GALR2, mGalRProtein level used designations for GALR2
- GAL2-R
- GALR-2
- galanin receptor type 2
- galanin receptor 2
- galanin receptor type 2-like
- galactose operon repressor
- DNA-binding transcriptional regulator GalR
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