GADD45A 产品
(Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
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Featured GADD45A Categories
GADD45A 抗体
High quality antibodies with extensive validation data.
GADD45A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
GADD45A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GADD45A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN685432
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (2)
- (2)
Cat. No.
ABIN560584
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6261869
Quantity
100 μL
Datasheet
Datasheet
Recommended GADD45A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975062
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956310
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956311
Quantity
96 tests
Datasheet
Datasheet
Recommended GADD45A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354675
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354677
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3080304
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GADD45A Products
: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." in: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).: "Significance of S100P as a biomarker in diagnosis, prognosis and therapy of opisthorchiasis-associated cholangiocarcinoma." in: International journal of cancer. Journal international du cancer, (2015) (PubMed).
: "CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells." in: Genes & cancer, Vol. 6, Issue 5-6, pp. 220-30, (2015) (PubMed).
: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).
: "p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K-Akt pathways." in: The Journal of general virology, Vol. 94, Issue Pt 2, pp. 326-35, (2013) (PubMed).
: "Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis." in: Cell death & disease, Vol. 1, pp. e81, (2011) (PubMed).
: "Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target." in: Cancer research, Vol. 69, Issue 4, pp. 1527-35, (2009) (PubMed).
: "Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 5, pp. 471-80, (2008) (PubMed).
Synonyms and alternative names related to GADD45A
growth arrest and DNA damage inducible alpha L homeolog (gadd45a.L), growth arrest and DNA-damage-inducible, alpha, b (gadd45ab), growth arrest and DNA damage inducible alpha (GADD45A), growth arrest and DNA damage inducible alpha (gadd45a), growth arrest and DNA damage-inducible protein 45 (GADD45), growth arrest and DNA-damage-inducible 45 alpha (Gadd45a), growth arrest and DNA-damage-inducible, alpha (Gadd45a), AA545191, ddit1, Ddit1, DDIT1, gadd45, GADD45, Gadd45, gadd45a, GADD45A, MGC53491, zgc:91795Protein level used designations for GADD45A
- growth arrest and DNA-damage-inducible, alpha
- growth arrest and DNA damage-inducible protein GADD45 alpha
- growth arrest and DNA-damage-inducible protein 45 alpha
- growth arrest and DNA-damage-inducible protein alpha
- growth arrest and DNA damage-inducible protein 45
- Growth arrest and DNA-damage-inducible protein GADD45 alpha
- DDIT-1
- DNA damage-inducible transcript 1 protein
- DNA-damage inducible transcript 1
- DNA-damage-inducible transcript 1
- Gadd45alpha
- growth arrest and DNA-damage-inducible protein GADD45 alpha
- DNA damage-inducible transcript-1
- growth arrest and DNA-damage-inducible 45 alpha
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