GAB1 抗体
(GRB2-Associated Binding Protein 1 (GAB1))
The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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GAB1 抗体
High quality antibodies with extensive validation data.
Recommended GAB1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
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Cat. No.
ABIN6243205
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN3028687
Quantity
0.1 mL
Datasheet
Datasheet
Reactivity
Human
Application
DB
Validations
- (1)
Cat. No.
ABIN6241063
Quantity
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Datasheet
Datasheet
Latest Publications for our GAB1 Products
: "Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16895-904, (2013) (PubMed).: "Role of Gab1 in UV-induced c-Jun NH2-terminal kinase activation and cell apoptosis." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1531-9, (2004) (PubMed).
Synonyms and alternative names related to GAB1
growth factor receptor bound protein 2-associated protein 1 (Gab1), GRB2-associated binding protein 1 (Gab1), GRB2 associated binding protein 1 (GAB1), AA408973, AW107238Protein level used designations for GAB1
- GRB2-associated binder 1
- GRB2-associated-binding protein 1
- GRB2-associated binding protein 1 long isoform
- growth factor receptor bound protein 2-associated protein 1
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