(FXYD Domain Containing Ion Transport Regulator 3 (FXYD3))
This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008].
Okudela, Yazawa, Ishii, Woo, Mitsui, Bunai, Sakaeda, Shimoyamada, Sato, Tajiri, Ogawa, Masuda, Sugimura, Kitamura: "Down-regulation of FXYD3 expression in human lung cancers: its mechanism and potential role in carcinogenesis." in: The American journal of pathology, Vol. 175, Issue 6, pp. 2646-56, (2009) (PubMed).
Aliases for FXYD3 抗体
FXYD domain containing ion transport regulator 3 (FXYD3) 抗体 FXYD domain-containing ion transport regulator 3 (Fxyd3) 抗体 FXYD3 抗体 MAT-8 抗体 MAT8 抗体 Mat8 抗体 PLML 抗体