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FRS2 蛋白

(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 1-341) protein (GST tag) Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 1-341) protein (GST tag) Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 1-341) protein (GST tag) (ABIN1354441)

FRS2 宿主: 人 宿主: 小麦胚 Recombinant AA, AP, ELISA, WB

Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 2-508) protein (His tag) Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 2-508) protein (His tag) Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 2-508) protein (His tag) (ABIN3080265)

Crystallography grade FRS2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 2-508) protein (His tag) Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 2-508) protein (His tag) Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 2-508) protein (His tag) (ABIN3125606)

Crystallography grade FRS2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

FRS2 蛋白 by Grade

Find FRS2 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

FRS2 蛋白 by Origin

Find FRS2 蛋白 for a variety of species such as anti-Human FRS2, anti-Mouse FRS2, anti-Rat FRS2. The species listed below are among those available. Click on a link to go to the corresponding products.

FRS2 蛋白 by Source

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FRS2 蛋白 by 蛋白类型

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FRS2 蛋白 by 应用范围

Find FRS2 蛋白 validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular FRS2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354439
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009430
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3009429
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2721422
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7122957
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7082062
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7082064
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7082063
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our FRS2 蛋白

Krejci, Salazar, Goodridge, Kashiwada, Schibler, Jelinkova, Thompson, Wilcox: "STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes." in: Journal of cell science, Vol. 121, Issue Pt 3, pp. 272-81, (2008) (PubMed).

Krejci, Masri, Salazar, Farrington-Rock, Prats, Thompson, Wilcox: "Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2929-36, (2007) (PubMed).

Aliases for FRS2 蛋白

fibroblast growth factor receptor substrate 2 (FRS2) 蛋白
fibroblast growth factor receptor substrate 2b (frs2b) 蛋白
fibroblast growth factor receptor substrate 2 (Frs2) 蛋白
4732458E18 蛋白
C330018A15Rik 蛋白
frs2 蛋白
FRS2A 蛋白
FRS2alpha 蛋白
Frs2alpha 蛋白
SNT 蛋白
SNT-1 蛋白
SNT1 蛋白
wu:fd21h10 蛋白
zgc:91973 蛋白
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