FRS2 蛋白
(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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10 results
FRS2
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AA, AP
1 image
2 references
FRS2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
FRS2
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
FRS2
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
FRS2
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 %
WB, SDS, Imm, PC
FRS2
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our FRS2 蛋白
: "STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes." in: Journal of cell science, Vol. 121, Issue Pt 3, pp. 272-81, (2008) (PubMed).: "Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2929-36, (2007) (PubMed).
Aliases for FRS2 蛋白
fibroblast growth factor receptor substrate 2 (FRS2) 蛋白fibroblast growth factor receptor substrate 2b (frs2b) 蛋白
fibroblast growth factor receptor substrate 2 (Frs2) 蛋白
4732458E18 蛋白
C330018A15Rik 蛋白
frs2 蛋白
FRS2A 蛋白
FRS2alpha 蛋白
Frs2alpha 蛋白
SNT 蛋白
SNT-1 蛋白
SNT1 蛋白
wu:fd21h10 蛋白
zgc:91973 蛋白
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