The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin\; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008].
Suman, Mishra, Chander: "High expression of FBP17 in invasive breast cancer cells promotes invadopodia formation." in: Medical oncology (Northwood, London, England), Vol. 35, Issue 5, pp. 71, (2018) (PubMed).
Hu, Mukhopadhyay, Craig: "Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness." in: The Journal of biological chemistry, Vol. 286, Issue 3, pp. 2261-72, (2011) (PubMed).
Kamioka, Fukuhara, Sawa, Nagashima, Masuda, Matsuda, Mochizuki: "A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 40091-9, (2004) (PubMed).
Aliases for FNBP1 抗体
formin binding protein 1 (FNBP1) 抗体 formin binding protein 1 (fnbp1) 抗体 formin binding protein 1 (Fnbp1) 抗体 formin binding protein 1 L homeolog (fnbp1.L) 抗体 1110057E06Rik 抗体 2210010H06Rik 抗体 FBP1 抗体 FBP17 抗体 Fbp17 抗体 MGC122623 抗体 MGC146466 抗体