FMO5 产品
(Flavin Containing Monooxygenase 5 (FMO5))
Categories
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009].
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Featured FMO5 Categories
Recommended FMO5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7149965
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
- (1)
Cat. No.
ABIN1881348
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN6140714
Quantity
100 μL
Datasheet
Datasheet
Recommended FMO5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6236377
Quantity
96 tests
Datasheet
Datasheet
Recommended FMO5 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7556837
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7547706
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354252
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our FMO5 Products
: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." in: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).: "Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 31, Issue 2, pp. 187-93, (2003) (PubMed).
: "Characterization of flavin-containing monooxygenase 5 (FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog." in: Archives of biochemistry and biophysics, Vol. 317, Issue 1, pp. 275-84, (1995) (PubMed).
Synonyms and alternative names related to FMO5
flavin containing monooxygenase 5 S homeolog (fmo5.S), flavin containing monooxygenase 5 (fmo5), flavin containing monooxygenase 5 (MCYG_00559), flavin containing monooxygenase 5 (FMO5), flavin containing monooxygenase 5 (Fmo5), 5033418D19Rik, AI195026, MGC68633, MGC108355, sb:cb1007, wu:fc05b01, wu:fk47g04Protein level used designations for FMO5
- flavin containing monooxygenase 5
- Dimethylaniline monooxygenase 5
- dimethylaniline monooxygenase [N-oxide-forming] 5-like
- FMO 5
- dimethylaniline monooxygenase [N-oxide-forming] 5
- dimethylaniline oxidase 5
- hepatic flavin-containing monooxygenase 5
- FMO 1C1
- FMO form 3
- dimethylanaline monooxygenase
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