FGF8 抗体
(Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008].
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Latest Publications for our FGF8 抗体
: "Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 2929-36, (2017) (PubMed).: "CMV-induced pathology: pathway and gene-gene interaction analysis." in: Experimental and molecular pathology, Vol. 97, Issue 1, pp. 154-65, (2014) (PubMed).
: "In vitro characterization of cardiac radiofrequency ablation lesions using optical coherence tomography." in: Optics express, Vol. 18, Issue 3, pp. 3079-92, (2010) (PubMed).
: "Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development." in: Developmental biology, Vol. 347, Issue 1, pp. 92-108, (2010) (PubMed).
: "FGF8 acts as a classic diffusible morphogen to pattern the neocortex." in: Development (Cambridge, England), Vol. 137, Issue 20, pp. 3439-48, (2010) (PubMed).
: "Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 239, Issue 9, pp. 2319-29, (2010) (PubMed).
: "BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation." in: Development (Cambridge, England), Vol. 137, Issue 18, pp. 3025-35, (2010) (PubMed).
: "Fibroblast growth factor 8 is expressed at higher levels in lactating human breast and in breast cancer." in: British journal of cancer, Vol. 86, Issue 7, pp. 1097-103, (2002) (PubMed).
Aliases for FGF8 抗体
fibroblast growth factor 8 (Fgf8) 抗体fibroblast growth factor 8 (FGF8) 抗体
Aigf 抗体
AIGF 抗体
Fgf-8 抗体
FGF-8 抗体
HBGF-8 抗体
HH6 抗体
KAL6 抗体
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