FGD1 抗体
(FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011].
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Latest Publications for our FGD1 抗体
: "MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice." in: The Journal of clinical investigation, Vol. 121, Issue 11, pp. 4383-92, (2011) (PubMed).
Aliases for FGD1 抗体
FYVE, RhoGEF and PH domain containing 1 (FGD1) 抗体FYVE, RhoGEF and PH domain containing 1 (Fgd1) 抗体
FYVE, RhoGEF and PH domain containing 1 (fgd1) 抗体
AAS 抗体
FGDY 抗体
MRXS16 抗体
ZFYVE3 抗体
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