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FGD1 抗体 (AA 508-558)

This 兔 多克隆 antibody specifically detects FGD1 in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN8121548
发货至: 中国
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Quick Overview for FGD1 抗体 (AA 508-558) (ABIN8121548)

抗原

See all FGD1 抗体
FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

适用

  • 11
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
人, 小鼠

宿主

  • 11
兔

克隆类型

  • 11
多克隆

标记

  • 11
This FGD1 antibody is un-conjugated

应用范围

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 4
    • 3
    • 1
    • 1
    AA 508-558

    原理

    FGD1 Antibody

    特异性

    This antibody detects endogenous levels of FGD1 at Human/Mouse

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from human FGD1 AA range: 508-558

    亚型

    IgG
  • 应用备注

    WB 1:500-2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

    别名

    FGD1

    背景

    Synonyms: FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)

    Background: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011],

    Gene Name: FGD1 FGDY ZFYVE3

    Protein Name: FGD1

    基因ID

    2245

    UniProt

    P98174

    途径

    Neurotrophin Signaling Pathway
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