FGD1 抗体 (AA 508-558)
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Quick Overview for FGD1 抗体 (AA 508-558) (ABIN8121548)
抗原
See all FGD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 508-558
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原理
- FGD1 Antibody
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特异性
- This antibody detects endogenous levels of FGD1 at Human/Mouse
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human FGD1 AA range: 508-558
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亚型
- IgG
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应用备注
- WB 1:500-2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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别名
- FGD1
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背景
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Synonyms: FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)
Background: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011],
Gene Name: FGD1 FGDY ZFYVE3
Protein Name: FGD1
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基因ID
- 2245
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UniProt
- P98174
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途径
- Neurotrophin Signaling Pathway
抗原
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